Outlook for Mac works with Microsoft Exchange, Microsoft 365, (including Hotmail and MSN), Gmail, Yahoo Mail, and iCloud Learn more about Microsoft 365 Microsoft 365 is a cloud-based subscription service that brings together premium versions of Word, Excel, PowerPoint, Outlook and OneDrive, with the best tools for the way people. Add a new Profile: Click the Create a new profile + button. Rename an existing profile: Double-click the profile.
Note: rename the old.ost or create a new profile with a different name, this forces outlook to create a new.ost. Open Contents SharedSupport, and then launch Outlook Profile Manager.
Additionally, using a mail identity or profile that is located on an external hard disk or on a network is not supported in either version of Outlook for Mac. We do not recommend that you change the default location of your Profile folder for Microsoft Outlook 2016 for Mac, or your Identity folder for Microsoft Outlook for Mac 2011 to an external hard disk or to a network.